๐ฉบ ่็ๆคๆ็กใงๆฏ่ผใใๆ ขๆงBๅ่็ใฎ่จๅบ็นๆง
ๆ ขๆงBๅ่็๏ผCHB๏ผใฏใไธ็ไธญใงๅบใ่ฆใใใ่็พๆฃใฎไธใคใงใใ็นใซใ่็ๆคใๅใใๆฃ่ ใจๅใใฆใใชใๆฃ่ ใฎ้ใงใใฉใฎใใใช่จๅบ็นๆงใฎ้ใใใใใฎใใ็ฅใใใจใฏใๆฒป็ๆน้ใๆฑบๅฎใใไธใง้่ฆใงใใๆฌ่จไบใงใฏใXiong Yeใใฎ็ ็ฉถใๅบใซใ่็ๆคใฎๆ็กใซใใๆ ขๆงBๅ่็ๆฃ่ ใฎ่จๅบ็นๆงใซใคใใฆ่ฉณใใ่งฃ่ชฌใใพใใ
๐ ็ ็ฉถๆฆ่ฆ
ใใฎ็ ็ฉถใฏใ่็ๆคใๅใใๆ ขๆงBๅ่็ใฎๆฃ่ ใจๅใใฆใใชใๆฃ่ ใฎ่จๅบ็นๆงใๆฏ่ผใใใใจใ็ฎ็ใจใใฆใใพใใ2928ไบบใฎๆชๆฒป็ใฎๆ ขๆงBๅ่็ๆฃ่ ใๅฏพ่ฑกใจใชใใAASLD 2018ใฎใฌใคใใฉใคใณใซๅบใฅใใฆไธ็ขบๅฎๆใ็นๅฎใใใพใใใ
๐ฌ ๆนๆณ
็ ็ฉถใฏๅพใๅใใซ่กใใใ2928ไบบใฎๆ ขๆงBๅ่็ๆฃ่ ใๅฏพ่ฑกใจใชใใพใใใๆฃ่ ใฎๅนด้ฝขใๆงๅฅใHBV DNAใฌใใซใ่็กฌๅบฆใชใฉใฎใใผใฟใๅ้ใใใ่็ๆคใๅใใๆฃ่ ใจๅใใฆใใชใๆฃ่ ใฎ้ใงๆฏ่ผใใใพใใใ
๐ ไธปใชใใคใณใ
| ้ ็ฎ | ่็ๆคใใ | ่็ๆคใชใ |
|---|---|---|
| ๆฃ่ ๆฐ | 288 (9.8%) | 2640 (90.2%) |
| ไธญๅคฎๅคๅนด้ฝข | 42.0ๆญณ | 39.0ๆญณ |
| HBV DNA (log10 IU/mL) | 3.4 | 2.7 |
| APRI | 0.42 | 0.36 |
| FIB-4 | 1.18 | 0.99 |
| ่็กฌๅบฆ (kPa) | 9.9 | 6.6 |
| ่กๅฐๆฟๆฐ (ร10^9/L) | 169.0 | 192.0 |
๐ญ ่ๅฏ
็ ็ฉถใฎ็ตๆใ่็ๆคใๅใใๆ ขๆงBๅ่็ๆฃ่ ใฏใๅนด้ฝขใ้ซใใHBV DNAใฌใใซใ่็กฌๅบฆใAPRIใFIB-4ใฎๅคใ้ซใใใจใ็คบใใใพใใใใพใใ่กๅฐๆฟๆฐใไฝใๆฃ่ ใฏ่็ๆคใๅใใๅฏ่ฝๆงใ้ซใใใจใๆใใใซใชใใพใใใใใใฏใ่็ๆคใๅฟ ่ฆใชๆฃ่ ใ็นๅฎใใใใใฎ้่ฆใชๆๆจใจใชใใพใใ
๐ก ๅฎ็ๆดปใขใใใคใน
- ๆ ขๆงBๅ่็ใฎใชในใฏ่ฆๅ ใ็่งฃใใๅฎๆ็ใชๆคๆปใๅใใใใจใ้่ฆใงใใ
- ่็ๆคใๅฟ ่ฆใใฉใใใฏใๅปๅธซใจ็ธ่ซใใๅใ ใฎ็ถๆณใซๅฟใใๅคๆญใ่กใใพใใใใ
- ๅฅๅบท็ใช็ๆดป็ฟๆ ฃใ็ถญๆใใใใจใงใ่่ใฎๅฅๅบทใๅฎใใใจใใงใใพใใ
โ ๏ธ ้็/่ชฒ้ก
ใใฎ็ ็ฉถใซใฏใใใคใใฎ้็ใใใใพใใใพใใๅพใๅใ็ ็ฉถใงใใใใใๅ ๆ้ขไฟใๆ็ขบใซใใใใจใฏ้ฃใใใงใใใพใใใตใณใใซใตใคใบใๅคงใใใใฎใฎใ่็ๆคใๅใใๆฃ่ ใฎๅฒๅใฏ้ๅธธใซไฝใใ็ตๆใไธ่ฌๅใใ้ใซใฏๆณจๆใๅฟ ่ฆใงใใ
ใพใจใ
่็ๆคใๅใใๆ ขๆงBๅ่็ๆฃ่ ใฏใๅนด้ฝขใ่ๆฉ่ฝใซใใใฆ้ก่ใช้ใใ่ฆใใใพใใใใใใใฎ็ตๆใฏใไปๅพใฎๆฒป็ๆน้ใๆฃ่ ็ฎก็ใซใใใฆ้่ฆใชๆ้ใจใชใใงใใใใ
้ข้ฃใชใณใฏ้
ๅ่ๆ็ฎ
| ๅ้ก | Clinical Characteristics of Indeterminate Chronic Hepatitis B Patients With and Without Liver Biopsy. |
|---|---|
| ๆฒ่ผ่ช(ๅนด) | Hepatol Res (2025 Dec 13) |
| DOI | doi: 10.1111/hepr.70094 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41389326/ |
| PMID | 41389326 |
ๆธ่ชๆ ๅ ฑ
| DOI | 10.1111/hepr.70094 |
|---|---|
| PMID | 41389326 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41389326/ |
| ็บ่กๅนด | 2025 |
| ่่ ๅ | Xiong Ye, Wang Jian, Song Yuchen, Fan Tao, Zhu Li, Zhang Shaoqiu, Jiang Chao, Liu Jiacheng, Yin Shengxia, Tong Xin, Xia Juan, Yan Xiaomin, Chen Yuxin, Shi Yu, Qiu Yuanwang, Zhu Chuanwu, Liu Xingxiang, Wu Chao, Huang Rui |
| ่่ ๆๅฑ | Department of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China. / School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China. / Department of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China. / Department of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. / Department of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, China. / Institute of Viruses and Infectious Diseases, Nanjing University, Nanjing, China. / State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. / Department of Infectious Diseases, The Fifth People's Hospital of Wuxi, Wuxi, China. / Department of Clinical Laboratory, Huai'an No. 4 People's Hospital, Huai'an, China. |
| ้่ชๅ | Hepatology research : the official journal of the Japan Society of Hepatology |