アレルギー性喘息の治療に既存薬を再利用する研究:ペンドリン阻害剤の探索
Repurposing approved drugs as Pendrin (SLC26A4) inhibitors in allergic asthma: single-cell nomination, structure-based screening and functional validation.
書誌情報
| DOI | 10.3389/fphar.2026.1926844 |
|---|---|
| PMID | 42812201 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42812201/ |
| 発行年 | 2026 |
| 著者名 | Lai Jianxing, Zhao Duoduo, Wang Xuwen, Wang Binben, Nan Jinliang |
| 雑誌名 | Front Pharmacol |
呼吸器疾患の治療研究:細胞内の脂肪とミトコンドリアの接点が新たな薬の標的になる可能性
Lipid droplet-mitochondria contact sites as druggable spatial-pharmacology targets in respiratory disease: cross-cell-type mechanisms and translational strategies.
書誌情報
| DOI | 10.3389/fcell.2026.1935993 |
|---|---|
| PMID | 42769092 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42769092/ |
| 発行年 | 2026 |
| 著者名 | Li Shuting, Bai Rongrong |
| 雑誌名 | Front Cell Dev Biol |
カビが原因の難治性アレルギー性肺疾患:生物学的製剤の選び方と治療の工夫
A Case Report of Refractory Allergic Bronchopulmonary Aspergillosis: The Art of Selection, Discontinuation and Switching Biologics.
書誌情報
| DOI | 10.2147/JIR.S631869 |
|---|---|
| PMID | 42765085 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42765085/ |
| 発行年 | 2026 |
| 著者名 | Li Yaqian, Yang Shuo, Ren Saisai, Cao Pei, Zhang Zhiqing, Zhang Yakun |
| 雑誌名 | J Inflamm Res |
喘息患者のSNAIL1遺伝子とビタミンDの関連を調べた研究
Association Between SNAIL1 Gene Expression, SNAIL1 Genetic Variation, Vitamin D Receptor Gene Expression, and Vitamin-D Status Among Jordanian Asthmatic Patients.
書誌情報
| DOI | 10.2147/JMDH.S626532 |
|---|---|
| PMID | 42763710 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42763710/ |
| 発行年 | 2026 |
| 著者名 | Zatar Alaa M, Jarrar Yazun B, Hindash Zain K, Albtoosh Asma S, Al-Younes Ah... |
| 雑誌名 | J Multidiscip Healthc |
オリーブ花粉アレルギーが起きる分子レベルの仕組みの研究
Elucidating molecular mechanisms of allergic sensitization to olive pollen through transcriptomics.
書誌情報
| DOI | 10.3389/fimmu.2026.1735045 |
|---|---|
| PMID | 42761069 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42761069/ |
| 発行年 | 2026 |
| 著者名 | Chacón Pedro, Domínguez-Cereijo Leticia, Doukkali Bouchra, Fernández-Delgad... |
| 雑誌名 | Front Immunol |
アレルギーの経口免疫療法が免疫細胞の働きをどう変えるかの研究
Dynamic regulation of CD300b and CD300f on myeloid cells in oral immunotherapy.
書誌情報
| DOI | 10.1016/j.jacig.2026.100766 |
|---|---|
| PMID | 42740934 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42740934/ |
| 発行年 | 2026 |
| 著者名 | Epstein-Rigbi Na'ama, Itan Michal, Avlas Shmulik, Damari Eytan, Nachshon Li... |
| 雑誌名 | J Allergy Clin Immunol Glob |
キトサン-dsRNAがRNAiによるミツバチヘギダニ駆除の影響を高める研究
Chitosan-dsRNA improves tissue stability and delivery for RNAi-mediated Varroa destructor control.
書誌情報
| DOI | 10.1002/ps.71288 |
|---|---|
| PMID | 42717425 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42717425/ |
| 発行年 | 2026 |
| 著者名 | Kim Sanghyeon, Mahalle Rashmi Manohar, Jeong Hoe Nan, Seong Keon Mook |
| 雑誌名 | Pest Manag Sci |
インフルエンザウイルスによる真菌アレルギー喘息の悪化と好酸球の多様性、マウスでの研究
Single-Cell and Spatial Transcriptomics Define Eosinophil Heterogeneity during Influenza A Virus-induced Exacerbation of Fungal Allergic Asthma in C57BL/6 mice.
書誌情報
| DOI | pii: qiag120. doi: 10.1093/jleuko/qiag120 |
|---|---|
| PMID | 42707006 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42707006/ |
| 発行年 | 2026 |
| 著者名 | Veltri Anthony J, Wells Anthony J, Baus Magdaline, Mathur Sameer K, Samaras... |
| 雑誌名 | J Leukoc Biol |
腸と肺のつながりから見る、酪酸がCOPD(慢性閉塞性肺疾患)の炎症に与える影響の研究
Butyrate Regulating Inflammatory Responses in Chronic Obstructive Pulmonary Disease via the Gut-Lung Axis.
書誌情報
| DOI | 10.2147/COPD.S621848 |
|---|---|
| PMID | 42668962 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42668962/ |
| 発行年 | 2026 |
| 著者名 | Liu Qiang, Fu Qian, Sun Caiyuan, Liu Chanli, Xiong Chan, Chen Mei |
| 雑誌名 | Int J Chron Obstruct Pulmon Dis |
メポリズマブが重症好酸球性喘息の血液好酸球の遺伝子やタンパク質に与える影響の研究
Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma.
書誌情報
| DOI | 10.1111/all.70491 |
|---|---|
| PMID | 42655930 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42655930/ |
| 発行年 | 2026 |
| 著者名 | Miguéns-Suárez Pablo, Vázquez-Mera Sara, Martelo-Vidal Laura, Aparicio Mari... |
| 雑誌名 | Allergy |
80代で発症した珍しい皮膚の良性腫瘍、毛母腫の報告
Pilomatricoma in an Octogenarian: A Case Report of an Exceptional Late-Life Presentation.
書誌情報
| DOI | 10.12659/AJCR.953320 |
|---|---|
| PMID | 42638289 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42638289/ |
| 発行年 | 2026 |
| 著者名 | Gunia Oliwia, Bresson Maëlys, Depardieu Claude, Dolivet Gilles, Gravante Gi... |
| 雑誌名 | Am J Case Rep |
腸内細菌と免疫が慢性肺疾患に与える影響:腸と肺のつながりの研究
Gut Microbiota-Immune Interactions in Chronic Lung Diseases: An Emerging Cross-Disease Perspective Gut-Lung Axis in Chronic Lung Disease.
書誌情報
| DOI | 10.2147/JIR.S605211 |
|---|---|
| PMID | 42633442 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42633442/ |
| 発行年 | 2026 |
| 著者名 | Zhu Qi, Zhang Chunyang, Niu Yulong, Lv Mingjin, Wang Biao, Pan Yao, Zhu Bin... |
| 雑誌名 | J Inflamm Res |
COPDと肺高血圧症の患者における血中HMGB1の役割の研究
Utility of serum HMGB1 in chronic obstructive pulmonary disease with pulmonary hypertension: A single-centre analysis.
書誌情報
| DOI | 10.1080/25310429.2026.2720837 |
|---|---|
| PMID | 42625546 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42625546/ |
| 発行年 | 2026 |
| 著者名 | Lv Qian, Yao Ruodi, Cheng Mengyu |
| 雑誌名 | Pulmonology |
喘息とCOPDが合併した患者の診断と治療の課題:4症例の報告
Diagnostic and Therapeutic Challenges in Asthma and Chronic Obstructive Pulmonary Disease Overlap: A Four-Patient Case Series.
書誌情報
| DOI | 10.7759/cureus.112821 |
|---|---|
| PMID | 42605492 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42605492/ |
| 発行年 | 2026 |
| 著者名 | Amalraj Benedict, Marrero Castillo Mariana, Gulati Neerja |
| 雑誌名 | Cureus |
手術前の好中球リンパ球比が心臓手術後の結果に与える影響の研究
Association between preoperative neutrophil-to-lymphocyte ratio and outcomes after deep hypothermic circulatory arrest: A cohort study of 1300 patients.
書誌情報
| DOI | 10.1016/j.xjon.2026.101810 |
|---|---|
| PMID | 42604332 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/42604332/ |
| 発行年 | 2026 |
| 著者名 | Gregg Alexander C, Ingason Arnar B, Feleke Nathnael, Krieger Katherine, Rot... |
| 雑誌名 | JTCVS Open |