2025.12.21

卵巣がんの薬剤耐性克服のための治療標的特定

An AI-driven multi-omics framework identifies lactylation-mediated therapeutic targets to overcome drug resistance in ovarian cancer.

書誌情報

DOI 10.1038/s41698-025-01150-x
PMID 41422325
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422325/
発行年 2025
著者名 Zhang Lijia, Guo Qi, Lei Xue, Yin Xinyu, Ling Yun, Liu Ye, Liu Songjiang
雑誌名 NPJ precision oncology
2025.12.21

[18]F-FAPI-74 PET/CTによる性腺および性腺外生殖細胞腫瘍の検査:パイロット研究

[F]F-FAPI-74 PET/CT for gonadal and extragonadal germ cell Tumors: a pilot study.

書誌情報

DOI 10.1186/s13550-025-01347-y
PMID 41422330
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422330/
発行年 2025
著者名 Kidess Marc, Siegmund Sophie C, Unterrainer Lena M, Kazmierczak Philipp, He...
雑誌名 EJNMMI research
2025.12.21

病原性変異によるPTPN13-β-カテニン相互作用の変化とB細胞受容体シグナルへの関与

Altered PTPN13-β-catenin interaction by pathogenic mutations and involvement of this axis in B-cell receptor signalling.

書誌情報

DOI 10.1038/s41598-025-33151-y
PMID 41422331
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422331/
発行年 2025
著者名 Cabrera-Riofrío David A, Li Hongbing, García-Calvo Clara, Sánchez-Bernal Ca...
雑誌名 Scientific reports
2025.12.21

ヨーロッパの大規模コホート研究による早期発症大腸がんリスク要因の先進的調査

A prospective investigation of early-onset colorectal cancer risk factors-pooled analysis of three large-scale European cohorts.

書誌情報

DOI 10.1038/s41416-025-03303-y
PMID 41422343
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422343/
発行年 2026
著者名 Laskar Ruhina S, Murphy Neil, Ferrari Pietro, Brennan Paul, Cross Amanda J,...
雑誌名 British journal of cancer
2025.12.21

膵臓がんと腫瘍内微生物叢:新しい治療への道

Intratumoral microbiome and pancreatic cancer: an enabling hallmark and path to novel treatments?

書誌情報

DOI 10.1038/s41416-025-03324-7
PMID 41422344
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422344/
発行年 2025
著者名 Carstensen Malte, Philipp Lisa-Marie, Basu Meghna, Hoffmann Patrick, Klenig...
雑誌名 British journal of cancer
2025.12.21

前立腺がんにおける骨盤リンパ節郭清の腫瘍学的利益のレベル1エビデンスはまだなし。PSMA PETスキャンでの陰性骨盤リンパ節の観

Pelvic lymph node dissection in prostate cancer, still no level 1 evidence of oncological benefit. Time to consider surveillance of negative pelvic lymph nodes on PSMA PET scan staging.

書誌情報

DOI 10.1038/s41391-025-01065-5
PMID 41422351
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422351/
発行年 2025
著者名 Yaxley J W
雑誌名 Prostate cancer and prostatic diseases
2025.12.21

大腸がんにおけるがん幹細胞様エクソソーム

Functional role of cancer stem cell like exosomes on survival and drug resistance behaviors of colorectal cancer cells.

書誌情報

DOI 10.1007/s12672-025-04295-0
PMID 41422355
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422355/
発行年 2025
著者名 Gheytanchi Elmira, Naseri Marzieh, Karimi-Busheri Feridoun, Tajik Fatemeh, ...
雑誌名 Discover oncology
2025.12.21

胃がん治療における二重キナーゼ阻害剤の相乗効果

The structure-preserving spectral graph neural network for dual kinase inhibitors and synergy scoring in gastric cancer.

書誌情報

DOI 10.1038/s41746-025-02240-7
PMID 41422356
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422356/
発行年 2025
著者名 Zhang Yang, Yuan Chunhong, Wang Longgang, Chen Yujia, Xing Yanpeng, Sun Yua...
雑誌名 NPJ digital medicine
2025.12.21

高齢者の下垂体腺腫手術:SEERデータの評価

Surgical management in very elderly patients with pituitary adenoma: a multivariable assessment of the surveillance, epidemiology, and end results database.

書誌情報

DOI 10.1007/s11102-025-01612-2
PMID 41422357
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422357/
発行年 2025
著者名 Gould Jacob, Singh Arjit, Patel Saarang, Yaffe Noah, Li Guan, Blanpain Lou,...
雑誌名 Pituitary
2025.12.21

海洋生物由来の環状ジペプチドの医学的特性

Prediction and Assessment of Anticancer, Antiproliferative, Pharmacokinetic Properties, and Human Serum Albumin Binding Propensity of a New Bioactive Marine Cyclic Dipeptide from Exiguobacterium profundum.

書誌情報

DOI 10.1007/s10126-025-10549-3
PMID 41422366
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41422366/
発行年 2025
著者名 Shankar Sriram, Tripathi Diksha, Nayak Subhashree Subhasmita, Krishna Ramad...
雑誌名 Marine biotechnology (New York, N.Y.)
2025.12.20

デジタル乳房画像の形態学的およびテクスチャ記述子の解析:人工ニューラルネットワークを用いた乳がん検出の支援

Morphological and textural descriptors analysis of digital mammograms with radiological findings to support breast cancer detection using artificial neural networks.

書誌情報

DOI 10.1088/2057-1976/ae2f65
PMID 41418324
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41418324/
発行年 2026
著者名 Trujillo-Zamudio F E, Palma-Garzón M V, Hernández-Campos M E, León-Marroquí...
雑誌名 Biomedical physics & engineering express
2025.12.20

TARDBPがGJB2を活性化し、肝細胞がんを促進

TARDBP upregulates GJB2 to promote tumor progression in hepatocellular carcinoma.

書誌情報

DOI 10.1016/j.bbrc.2025.153123
PMID 41418351
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41418351/
発行年 2026
著者名 Zhu Yuhong, Hu Mingchao, Xu Rongcan, Zhai Jinlong, Yang Linlin, Jin Xingtao
雑誌名 Biochemical and biophysical research communications
2025.12.20

慢性骨髄性白血病治療のための潜在的な化合物の特定:分子ドッキングと分子動力学シミュレーション手法

Targeting myeloid cell leukemia-1 protein to identify potential compounds for chronic myeloid leukemia treatment: Molecular docking and molecular dynamics simulation approaches.

書誌情報

DOI 10.1016/j.bbrc.2025.153115
PMID 41418352
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41418352/
発行年 2026
著者名 Singh Pratistha, Singh Vinay Kumar, Verma Malkhey
雑誌名 Biochemical and biophysical research communications
2025.12.20

トルコのニリュファー川のPAHs分布と発がんリスク

Distribution, sediment retention, and carcinogenic risk of polycyclic aromatic hydrocarbons (PAHs) in an urban-industrial river system (Nilüfer Stream, Türkiye).

書誌情報

DOI 10.1016/j.marpolbul.2025.119149
PMID 41418377
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41418377/
発行年 2026
著者名 Sari Mehmet Ferhat, Esen Fatma
雑誌名 Marine pollution bulletin
2025.12.20

子宮頸がん対策:HPVワクチン、検査、治療の影響

Elimination of cervical cancer: the impact of HPV vaccination, primary HPV screening, and expanded access to cancer treatment services.

書誌情報

DOI 10.1016/j.mam.2025.101423
PMID 41418380
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41418380/
発行年 2026
著者名 Hall Michaela T, Hyatt Amelia, Smith Megan A, Torode Julie, Costa Telma, Ng...
雑誌名 Molecular aspects of medicine