ETC-501が脳内に浸透するMNKキナーゼ阻害剤で、TMZ誘導老化を増強し、グリオブラストーマ細胞を老化細胞療法に感受性を高める
ETC-501 is a Brain Penetrant MNK Kinase Inhibitor that Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.
書誌情報
| DOI | 10.1158/0008-5472.CAN-24-4388 |
|---|---|
| PMID | 41570320 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570320/ |
| 発行年 | 2026 |
| 著者名 | Nah Giselle Sek Suan, Chong Yuk Kien, Sulaimi Fatin Nasha, Lee Kian Leong, ... |
| 雑誌名 | Cancer research |
細胞と核のサイズが染色体不安定性と腫瘍性と関連する
Cell and Nuclear Size are Associated with Chromosomal Instability and Tumorigenicity in Cancer Cells that Undergo Whole Genome Doubling.
書誌情報
| DOI | 10.1158/0008-5472.CAN-24-3718 |
|---|---|
| PMID | 41570321 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570321/ |
| 発行年 | 2026 |
| 著者名 | Bloomfield Mathew, Huth Sydney M, McCausland Daniella S, Saad Ron, Bano Naz... |
| 雑誌名 | Cancer research |
肝細胞がんにおけるPD-1ブロックエイドへの感受性を高める腫瘍内乳酸菌のCD8+ T細胞増加影響
Intratumoral Lactobacillus johnsonii Enhances Sensitivity to PD-1 Blockade by Inducing CD8+ T Cell Expansion in Hepatocellular Carcinoma.
書誌情報
| DOI | 10.1158/0008-5472.CAN-25-0346 |
|---|---|
| PMID | 41570324 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570324/ |
| 発行年 | 2026 |
| 著者名 | Liu Qianshi, Liu Yiqiang, Zhou Yue, Liang Liang, Wan Yejian, Wang Ying, Hua... |
| 雑誌名 | Cancer research |
IDH1がナソファリンジアルカノーマにおける化学療法耐性を促進するために、クロマチンリモデリングとDHODH転写を誘導してヌクレオチド代謝を再
IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma.
書誌情報
| DOI | 10.1158/0008-5472.CAN-25-2313 |
|---|---|
| PMID | 41570327 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570327/ |
| 発行年 | 2026 |
| 著者名 | Zhao Yuheng, Ou Chunxian, Huang Huimin, Wang Yujue, Shen Jiaxi, Li Yaoyi, H... |
| 雑誌名 | Cancer research |
ACSL5が乳癌細胞の肺転移を促進
ACSL5 Mediates Adaptation to the Palmitic Acid-Enriched Pulmonary Microenvironment to Enhance Metastatic Breast Cancer Cell Survival and Lung Metastasis.
書誌情報
| DOI | 10.1158/0008-5472.CAN-25-0866 |
|---|---|
| PMID | 41570334 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570334/ |
| 発行年 | 2026 |
| 著者名 | Chen Shanchun, Chang Chao, Liu Xiaoqi, Wang Rui, Liu Yongcan, Meng Die, Wan... |
| 雑誌名 | Cancer research |
骨肉腫腫瘍モデルの薬剤応答の多様性
Patient-derived osteosarcoma tumoroid model reveals functional phenotypic diversity with implications for drug responses.
書誌情報
| DOI | 10.1088/1758-5090/ae3c44 |
|---|---|
| PMID | 41570341 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570341/ |
| 発行年 | 2026 |
| 著者名 | Bhatia Sugandha, Claxton Briony, Thompson Erik W, Lowe Martin, Wagels Micha... |
| 雑誌名 | Biofabrication |
乳がんサバイバーにおけるマインドフルネスの影響
Effectiveness of mindfulness-based interventions on quality of life in women breast cancer survivors: a systematic review and meta-analysis.
書誌情報
| DOI | 10.1016/j.breast.2026.104701 |
|---|---|
| PMID | 41570361 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570361/ |
| 発行年 | 2026 |
| 著者名 | Tenorio do Amaral Paulo Gustavo, Tosello Giuliano Tavares, Silva Filho Pedr... |
| 雑誌名 | Breast (Edinburgh, Scotland) |
多角的解析が示す、N-結合先天性糖鎖合成障害の2つの内皮細胞モデルにおけるERストレスの主要な特徴
Multi-omics analysis reveals ER stress as a main feature in two endothelial cell models of N-linked congenital disorders of glycosylation.
書誌情報
| DOI | 10.1016/j.ymgme.2026.109737 |
|---|---|
| PMID | 41570364 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570364/ |
| 発行年 | 2026 |
| 著者名 | Driesen Karen, Holubová Veronika, Magalhães Pedro, Loopmans Shauni, Guharoy... |
| 雑誌名 | Molecular genetics and metabolism |
手術後のOIRD：予防と定義の革新
Improving definitions and innovations for identification and prevention of postoperative opioid-induced respiratory depression (OIRD): Proceedings of the International Consensus Conference.
書誌情報
| DOI | 10.1016/j.jclinane.2026.112133 |
|---|---|
| PMID | 41570366 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570366/ |
| 発行年 | 2026 |
| 著者名 | Urman Richard D, Taenzer Andreas H, Dahan Albert, Turan Alparslan, Abdelmal... |
| 雑誌名 | Journal of clinical anesthesia |
がん最新研究速報（2026年2月）
OncoFlash: Research Updates in a Flash! (Feb 2026 Edition).
書誌情報
| DOI | 10.1016/j.clon.2026.104034 |
|---|---|
| PMID | 41570367 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41570367/ |
| 発行年 | 2026 |
| 雑誌名 | Clin Oncol (R Coll Radiol) (2026 Jan 6) |
Rhazya strictaの化学成分：HER2陰性乳がんを標的としたAurora kinase A阻害剤としての潜在性についての総合的な研究
Chemical constituents of Rhazya stricta as potential Aurora kinase A inhibitors for targeting HER2-negative breast cancer: an integrated in-silico and in-vitro study.
書誌情報
| DOI | 10.1186/s12906-025-05218-w |
|---|---|
| PMID | 41566300 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41566300/ |
| 発行年 | 2026 |
| 著者名 | Yusaf Ikhlas, Malik Nirmal, Ahmed Abrar, Saeed Hamid |
| 雑誌名 | BMC complementary medicine and therapies |
皮膚科教育の比較研究：高・低発生地域の事例
A comparative study of dermatology education in high and low prevalence areas: Kuwait University and the University of Aberdeen.
書誌情報
| DOI | 10.1186/s12909-026-08615-y |
|---|---|
| PMID | 41566301 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41566301/ |
| 発行年 | 2026 |
| 著者名 | AlMulla Lulwa |
| 雑誌名 | BMC medical education |
piR-1170が三重否定型乳がんにおける脳転移と免疫回避を促進：WTAPによるm6Aメチル化再プログラミング
piR-1170 drives brain metastasis and immune evasion via WTAP-mediated m6A methylation reprogramming in triple-negative breast cancer.
書誌情報
| DOI | 10.1186/s12943-026-02568-y |
|---|---|
| PMID | 41566302 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41566302/ |
| 発行年 | 2026 |
| 著者名 | Luo Yongzhou, Tian Wenwen, Zhu Xudong, Wei Weidong, Ye Feng, Situ Min-Yi, Y... |
| 雑誌名 | Molecular cancer |
悪性黒色腫におけるCCN1の意義
Circulating cellular communication network factor 1 (CCN1) as a liquid biopsy marker indicating progression in advanced melanoma.
書誌情報
| DOI | 10.1186/s12967-026-07724-y |
|---|---|
| PMID | 41566306 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41566306/ |
| 発行年 | 2026 |
| 著者名 | Heidrich Isabel, Reese Kim-Lea, Ullemeyer Helen, Kött Julian, Freiberg Hann... |
| 雑誌名 | Journal of translational medicine |
アザシチジンとPIM-2阻害剤による核因子κB経路抑制による骨髄異形成症候群細胞の協力的なアポトーシス誘導
Synergistic apoptosis induction in myelodysplastic syndrome cells by azacitidine and PIM-2 inhibitors via nuclear factor-kappa B pathway inhibition.
書誌情報
| DOI | 10.1186/s12885-025-14657-0 |
|---|---|
| PMID | 41566307 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41566307/ |
| 発行年 | 2026 |
| 著者名 | Guo Yixuan, Liu Zhaoyun, Lei Wenhui, Liu Xiaohan, Yang Chun, Ding Kai, Fu R... |
| 雑誌名 | BMC cancer |