2026.01.18

がん細胞とがん幹細胞の特徴を明らかに

Heterogeneity of glucose metabolism and uptake identifies distinct cancer cell and cancer stem cell phenotypes.

書誌情報

DOI 10.1186/s11658-025-00837-0
PMID 41547734
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41547734/
発行年 2026
著者名 Tylichova Zuzana, Krkoska Martin, Hrabal Vaclav, Stenckova Michaela, Vojtes...
雑誌名 Cellular & molecular biology letters
2026.01.18

脂肪幹細胞と3Dプリントスキャフォールドの研究

Experimental study on the in vitro osteogenic and chondrogenic ability of fat stem cells combined with 3D-printed porous scaffolds.

書誌情報

DOI 10.1186/s12891-025-09476-0
PMID 41547791
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41547791/
発行年 2026
著者名 He Yinhao, Li Xiaosheng, Tu Zhixing, Chen Hongwen, Zeng Hui, Peng Qiang, Ch...
雑誌名 BMC musculoskeletal disorders
2026.01.18

Trefoil Factor 1と乳がんの関連

Low tumoral Trefoil Factor 1 expression relates to aggressive tumor features and poor survival in young women with breast cancer.

書誌情報

DOI 10.1038/s41598-026-36341-4
PMID 41547953
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41547953/
発行年 2026
著者名 Kvamme Amalie B, Hugaas Ulrikke, Sæle Anna K M, Ingebriktsen Lise M, Svanøe...
雑誌名 Scientific reports
2026.01.18

CDK8阻害が虚血性骨折治癒の改善をもたらす

Inhibition of CDK8 rescues impaired ischemic fracture healing.

書誌情報

DOI 10.1038/s41536-026-00456-z
PMID 41547960
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41547960/
発行年 2026
著者名 Capobianco Christina A, Song Michelle J, Farrell Easton C, Knights Alexande...
雑誌名 NPJ Regenerative medicine
2026.01.18

CD73遺伝子の過剰発現が神経原性膀胱ラットにおけるNFκB/NLRP3/caspase-1シグナル経路を調節し、膀胱修復を促進する

CD73 overexpression in ADSCs accelerates bladder repair by regulating the NFκB/NLRP3/caspase-1 signaling axis in neurogenic bladder rats.

書誌情報

DOI 10.1038/s41536-026-00454-1
PMID 41547984
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41547984/
発行年 2026
著者名 Zhu Guanqun, Zhang Rui, Huang Jiao, Zhang Zongliang, Zhao Kai, Yin Xinbao, ...
雑誌名 NPJ Regenerative medicine
2026.01.17

PLN-R14del変異による遺伝性心疾患の治療におけるPLN-L31A/I40Aの影響

PLN-L31A/I40A for the treatment of inherited heart disease caused by PLN-R14del mutations.

書誌情報

DOI 10.1038/s41401-025-01711-7
PMID 41545752
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41545752/
発行年 2026
著者名 Chen Zi-Yang, Guo Ren, Wang Min, Ji Si-Jia, Zhang Jing-Wei, Zheng Hui-Xiang...
雑誌名 Acta pharmacologica Sinica
2026.01.17

遺伝子融合による皮膚の間葉系腫瘍:最新の注目点

Gene fusion-driven cutaneous mesenchymal neoplasms: An updated review emphasizing the emerging entities.

書誌情報

DOI 10.1007/s00428-025-04394-x
PMID 41545801
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41545801/
発行年 2026
著者名 Cazzato Gerardo, Fortarezza Francesco, Daruish Maged, Annese Tiziana, Ribat...
雑誌名 Virchows Archiv : an international journal of pathology
2026.01.17

軟骨関節炎をCD59依存性経路で補完活性を抑制する間葉系幹細胞エクソソーム

Mesenchymal stem cell exosomes alleviate osteoarthritis by inhibiting complement activation via a CD59-dependent pathway.

書誌情報

DOI 10.1186/s13075-026-03730-z
PMID 41545893
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41545893/
発行年 2026
著者名 Jiang Yuanyuan, Ng Chiew Yong, Seow Dexter Shi Kai, Loh Jia Tong, Wong Raym...
雑誌名 Arthritis research & therapy
2026.01.17

疾患モデリングと治療におけるオルガノイドの最新技術

Organoids for disease modeling and treatment: state-of-the-art.

書誌情報

DOI 10.1186/s40164-026-00743-x
PMID 41545895
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41545895/
発行年 2026
著者名 Xu Mingyi, Kong Dexiao, Sun Shan, Wang Yuanxin, Su Gang, Zhang Shanshan, Ya...
雑誌名 Experimental hematology & oncology
2026.01.17

ヒト臍帯間葉系幹細胞の骨形成分化を促進するLncRNA TUG1の役割

LncRNA TUG1 promotes osteogenic differentiation of human umbilical cord mesenchymal stem cells by regulating miR-138/SIRT1 axis.

書誌情報

DOI 10.1186/s13018-025-06593-3
PMID 41546042
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41546042/
発行年 2026
著者名 Ma Pengcheng, Chen Huizhi, Zhao Jing, Zheng Jiachun, Gao Hongwei
雑誌名 Journal of orthopaedic surgery and research
2026.01.17

Notchシグナル活性化が人間多能性幹細胞由来のCNS様内皮細胞における小胞内膜内輸送を減少させる

Notch signaling activation reduces vesicular endocytosis in human pluripotent stem cell-derived CNS-like endothelial cells.

書誌情報

DOI 10.1186/s12987-025-00754-6
PMID 41546116
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41546116/
発行年 2026
著者名 Boutom Sarah M, Walsh Luke D, Herman Maxwell M, Ding Yunfeng, Yaghoobi Hash...
雑誌名 Fluids and barriers of the CNS
2026.01.14

体細胞ゲノム編集の生物学的影響を監視

Monitoring biological effects of somatic cell genome editing.

書誌情報

DOI 10.1038/s41576-025-00916-0
PMID 41530266
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530266/
発行年 2026
著者名 Freedman Benjamin S, Bulte Jeff W M, Conklin Bruce R, Judge Luke M, Dwinell...
雑誌名 Nature reviews. Genetics
2026.01.14

細胞内小胞が網膜神経保護で薬物送達に優れる

Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection.

書誌情報

DOI 10.1038/s41551-025-01596-1
PMID 41530294
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530294/
発行年 2026
著者名 Zhang Hui, Yu Xinyue, Yang Fuhua, An Jinying, Su Lin, Liu Yuqing, Zhang Mi,...
雑誌名 Nature biomedical engineering
2026.01.14

BMSC由来の細胞外小胞が5′-tRF-GlyCCCを放出し、MAFLDのインスリン感受性を改善する

BMSC-derived extracellular vesicles affect gluconeogenesis and lipogenesis by releasing 5'-tRF-GlyCCC to improve MAFLD insulin sensitivity.

書誌情報

DOI 10.1007/s10565-025-10132-5
PMID 41530468
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530468/
発行年 2026
著者名 Yang Chenyun, Chen Huiling, Huang Xiaojing, Li Yanyan, Wen Song, Zhou Ligan...
雑誌名 Cell biology and toxicology
2026.01.14

多様な系統からの胎児の回帰が腸幹細胞プールを維持し、ストレスに強さをもたらす

Fetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience.

書誌情報

DOI 10.1038/s42003-026-09533-x
PMID 41530496
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530496/
発行年 2026
著者名 Kirino Sakura, Uefune Fumiya, Miyake Kensuke, Ogasawara Nobuhiko, Kobayashi...
雑誌名 Communications biology