アルツハイマー治療の革新的なアプローチ
From consortia discovery to biotech creation: An innovative approach to next-gen Alzheimer's drugs.
書誌情報
| DOI | 10.1002/alz.71165 |
|---|---|
| PMID | 41618124 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41618124/ |
| 発行年 | 2026 |
| 著者名 | Giardina Sarah F, Culver Alexander, Ahmed Chandrama, Mirescu Christian, Obl... |
| 雑誌名 | Alzheimer's & dementia : the journal of the Alzheimer's Association |
救急部での急性自発性脳内出血（ICH）の緊急対応
Acute management of spontaneous intracerebral hemorrhage (ICH) in the emergency department.
書誌情報
| DOI | 10.1186/s12245-026-01126-z |
|---|---|
| PMID | 41618143 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41618143/ |
| 発行年 | 2026 |
| 著者名 | Puissant Madeleine, Ganti Latha |
| 雑誌名 | International journal of emergency medicine |
中国人のMEF2A遺伝子変異と脳梗塞リスク
Association between MEF2A variants and ischemic stroke risk: a case-control study and two prospective cohort studies in a Chinese population.
書誌情報
| DOI | 10.1186/s12872-026-05537-x |
|---|---|
| PMID | 41618147 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41618147/ |
| 発行年 | 2026 |
| 著者名 | Fang Zhengmei, Chen Yan, Han Xu, Zhu Lijun, Du Mengxue, Jin Yuelong, Shen C... |
| 雑誌名 | BMC cardiovascular disorders |
CSFアルファシヌクレイン増幅アッセイの反応時間が、10年後のパーキンソン病の拡散悪性サブタイプを予測
Faster reaction times of CSF alpha-synuclein seed amplification assay predict the diffuse malignant subtype of Parkinson's disease at 10-year follow-up.
書誌情報
| DOI | 10.1177/1877718X261417468 |
|---|---|
| PMID | 41610263 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610263/ |
| 発行年 | 2026 |
| 著者名 | Grillo Piergiorgio, Riboldi Giulietta Maria, Pisani Antonio, Kang Un Jung, ... |
| 雑誌名 | Journal of Parkinson's disease |
非典型パーキンソン症候群における内視鏡下経皮的胃造口術の生存と誤嚥の結果
Percutaneous endoscopic gastrostomy in atypical parkinsonian syndromes: survival and aspiration outcomes from a retrospective international cohort.
書誌情報
| DOI | 10.26635/6965.7117 |
|---|---|
| PMID | 41610292 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610292/ |
| 発行年 | 2026 |
| 著者名 | Ruttle Tim, Jones Edward, Towns Cindy |
| 雑誌名 | The New Zealand medical journal |
脊髄性筋萎縮症の健康指標：疾患特異的な結果測定
The spinal and bulbar muscular atrophy-health index: a disease-specific outcome measure.
書誌情報
| DOI | 10.1080/21678421.2026.2620454 |
|---|---|
| PMID | 41610298 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610298/ |
| 発行年 | 2026 |
| 著者名 | Alqahtani Abdullah, Weinstein Jennifer, Kokkinis Angela, Schindler Alice B,... |
| 雑誌名 | Amyotrophic lateral sclerosis & frontotemporal degeneration |
ペニシリン結合タンパク質とテトラペプチドの環化
Biocatalytic Tetrapeptide Macrocyclization by Cryptic Penicillin-Binding Protein-Type Thioesterases.
書誌情報
| DOI | 10.1021/acs.biochem.5c00758 |
|---|---|
| PMID | 41610322 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610322/ |
| 発行年 | 2026 |
| 著者名 | Jeannette Paisley L, Budimir Zachary L, Johnson Lucas O, Parkinson Elizabet... |
| 雑誌名 | Biochemistry |
血液タンパク質とmiRNAの組み合わせ検出によるCRISPR-AD法は、アルツハイマー病の診断性能向上に貢献
CRISPR-AD: Combinational Detection of Blood Protein and miRNA with Digital CRISPR-Based Assay Enable to Improve the Diagnostic Performance of Alzheimer's Disease.
書誌情報
| DOI | 10.1021/acs.analchem.5c06080 |
|---|---|
| PMID | 41610326 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610326/ |
| 発行年 | 2026 |
| 著者名 | Guo Wenlong, Cheng Yingjie, Yin Haofan, Li Sheng, Wan Yunzhu, Li Chenzhong,... |
| 雑誌名 | Analytical chemistry |
脳卒中患者の手の浮腫を軽減する装置の機能評価
Functional Assessment of a Flexible Thermal Stimulation Device for Hand Edema Elimination in Stroke Survivors.
書誌情報
| DOI | 10.1109/TNSRE.2026.3659248 |
|---|---|
| PMID | 41610355 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610355/ |
| 発行年 | 2026 |
| 著者名 | Zhou Yitong, Zhang Jun, Li Yingying, Tang Congzhi, Yang Xi, Song Aiguo |
| 雑誌名 | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society |
血液バイオマーカーと神経病理学的基盤
Blood-Based Biomarkers and the Complexity of Neuropathologic Substrates of Alzheimer Disease and Related Disorders.
書誌情報
| DOI | 10.1212/WNL.0000000000214504 |
|---|---|
| PMID | 41610377 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610377/ |
| 発行年 | 2026 |
| 著者名 | Irwin David John |
| 雑誌名 | Neurology |
小児の出血性もやもや病：臨床経過、治療、結果
Pediatric Hemorrhagic Moyamoya Disease: Clinical Course, Treatment, and Outcomes.
書誌情報
| DOI | 10.1212/WNL.0000000000214612 |
|---|---|
| PMID | 41610378 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610378/ |
| 発行年 | 2026 |
| 著者名 | Guo Qingbao, Xie Manli, Wang Jingchun, Zhao Changfa, Wang Zhenhua, Zhang Ru... |
| 雑誌名 | Neurology |
アルツハイマー病と血中バイオマーカーの関連性
Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias.
書誌情報
| DOI | 10.1212/WNL.0000000000214351 |
|---|---|
| PMID | 41610380 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610380/ |
| 発行年 | 2026 |
| 著者名 | Kivisäkk Pia, Fatima Hadia, Wu Chao-Yi, Padmanabhan Nikhil, Romero Daniel, ... |
| 雑誌名 | Neurology |
パーキンソン病と電磁気関節動態センサー
The Effects of Electromagnetic Articulography Sensors on Speech in Individuals With and Without Parkinson's Disease.
書誌情報
| DOI | 10.1044/2025_JSLHR-25-00263 |
|---|---|
| PMID | 41610398 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41610398/ |
| 発行年 | 2026 |
| 著者名 | Thompson Austin, Hirsch Micah, Kim Yunjung |
| 雑誌名 | Journal of speech, language, and hearing research : JSLHR |
Alzheimer病関連タンパク質BIN1との結合を妨げるRIN3変異は、RAB5の過剰活性化と細胞内小胞の病態を引き起こす
mutations impairing binding of the Alzheimer's disease-associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology.
書誌情報
| DOI | 10.1126/sciadv.adx2127 |
|---|---|
| PMID | 41604486 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41604486/ |
| 発行年 | 2026 |
| 著者名 | Maaser-Hecker Anna K, Zellmer Jacob C, Kim Michelle, Bakiasi Grisilda, Mait... |
| 雑誌名 | Science advances |
α-シヌクレインシード増幅アッセイの認知症検査性能：4つの研究所での比較
Diagnostic Performance of the α-Synuclein Seed Amplification Assay for Dementia With Lewy Bodies: A Comparison Across 4 Laboratories.
書誌情報
| DOI | 10.1212/WNL.0000000000214614 |
|---|---|
| PMID | 41604609 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41604609/ |
| 発行年 | 2026 |
| 著者名 | Kumar Rakesh, Gravett Stephanie, Jelic Vesna, Lange Johannes, Oftedal Linn,... |
| 雑誌名 | Neurology |