DNA統合のための高効率組換え酵素の進化誘導
Directed evolution on compact landing pads yields highly efficient recombinases for large DNA integration.
書誌情報
| DOI | 10.1093/nar/gkaf1444 |
|---|---|
| PMID | 41495889 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495889/ |
| 発行年 | 2026 |
| 著者名 | Kim Hanseop, Kang Hyo-Gu, Oh Yeounsun, Lee Wi-Jae, Lee Youngjeon, Kim Eun-K... |
| 雑誌名 | Nucleic acids research |
ショウジョウバエ転写因子のβストランド二量体化
Beyond DNA binding: single C2H2 zinc fingers with adjacent β-strands mediate dimerization in Drosophila transcription factors.
書誌情報
| DOI | 10.1093/nar/gkaf1425 |
|---|---|
| PMID | 41495890 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495890/ |
| 発行年 | 2026 |
| 著者名 | Balagurov Konstantin I, Mariasina Sofia S, Dukhalin Sergey D, Sluchanko Nik... |
| 雑誌名 | Nucleic acids research |
核キャップ結合複合体のRNA処理と監視
The nuclear cap-binding complex regulates subcellular RNA processing and surveillance of coding and noncoding RNAs.
書誌情報
| DOI | 10.1093/nar/gkaf1467 |
|---|---|
| PMID | 41495891 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495891/ |
| 発行年 | 2026 |
| 著者名 | Ganguly Diep R, Gregory Brian D |
| 雑誌名 | Nucleic acids research |
ArgonauteによるRNA編集と点突然変異修復
Argonaute-mediated RNA editing selectively repairs point mutations.
書誌情報
| DOI | 10.1093/nar/gkaf1403 |
|---|---|
| PMID | 41495892 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495892/ |
| 発行年 | 2026 |
| 著者名 | Zhang Zhiwei, Wang Jinyue, Guo Tongyu, Yu Xiaolan, Wang Fei, Zhang Hang, Li... |
| 雑誌名 | Nucleic acids research |
RNAによるDNA転座を可能にするCRISPR-Cas影響因子の構造再配置
Sequential structural rearrangements at the PAM-distal site of a type I-F3 CRISPR-Cas effector enabling RNA-guided DNA transposition.
書誌情報
| DOI | 10.1093/nar/gkaf1415 |
|---|---|
| PMID | 41495894 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495894/ |
| 発行年 | 2026 |
| 著者名 | Ishihara Kazuki, Matsumoto Shunsuke, Gerle Christoph, Gopalasingam Chai C, ... |
| 雑誌名 | Nucleic acids research |
GIY-YIG核酸酵素の切断選好性の要因
Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.
書誌情報
| DOI | 10.1093/nar/gkaf1430 |
|---|---|
| PMID | 41495900 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495900/ |
| 発行年 | 2026 |
| 著者名 | Loedige Kurt W, Hall Mairwyn A, Ghimirey Sabin, Stead Brent E, Edgell David... |
| 雑誌名 | Nucleic acids research |
特定の抗生物質耐性遺伝子を持つ大腸菌株の影響的な殺菌と再感受性向上の研究
Specific killing and resensitization of pathogenic Escherichia coli strains carrying blaCTX-M-15 β-lactamase using targeted-antibacterial-plasmids (TAPs).
書誌情報
| DOI | 10.1093/nar/gkaf1466 |
|---|---|
| PMID | 41495909 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41495909/ |
| 発行年 | 2026 |
| 著者名 | Derollez Elisabeth, Roson-Calero Natalia, Rouzé Pauline, Dedieu-Berne Annic... |
| 雑誌名 | Nucleic acids research |
ベルベリンの砒素誘発心毒性治療効果を検証
Integrative Network Pharmacology and Molecular Docking-Based Validation of Berberine as a Therapeutic Agent in Arsenic-Induced Cardiotoxicity.
書誌情報
| DOI | 10.1007/s12012-025-10083-7 |
|---|---|
| PMID | 41489701 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489701/ |
| 発行年 | 2026 |
| 著者名 | Krishnamoorthy Saran, Veeraraghavan Vishnu Priya, Renu Kaviyarasi |
| 雑誌名 | Cardiovascular toxicology |
CD36の転写解析と急性骨髄性白血病
Integrative transcriptomics defines CD36 as a key regulator of immunometabolic signaling in acute myeloid leukemia.
書誌情報
| DOI | 10.1007/s13258-025-01728-6 |
|---|---|
| PMID | 41489721 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489721/ |
| 発行年 | 2026 |
| 著者名 | Ashaq Muhammad Sameer, Zhou Qian, Li Yanxia, Guo Meiqi, Zhang Shujing, Wang... |
| 雑誌名 | Genes & genomics |
DNA修復遺伝子とTP53共変異の免疫療法への非小細胞肺がん反応予測
The value of DNA repair gene and TP53 co-mutation in predicting the response of non-small cell lung cancer to immunotherapy.
書誌情報
| DOI | 10.1007/s12672-025-03775-7 |
|---|---|
| PMID | 41489765 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489765/ |
| 発行年 | 2026 |
| 著者名 | Ye Bin, Wu Chunzhi, Quan Xiaoying, Jia Xiaoli, Yao Lin, Lei Lei, Chen Xiaoy... |
| 雑誌名 | Discover oncology |
歯の埋伏と欠損の関連をAIで解析
Unlocking predictive genetic factors with artificial intelligence: relationship between dental impaction and hypodontia evaluated via association-rule algorithms: a case-control study.
書誌情報
| DOI | 10.1007/s44445-025-00109-9 |
|---|---|
| PMID | 41489795 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489795/ |
| 発行年 | 2026 |
| 著者名 | Alhazmi Nora, Alaqla Ali, Almuzzaini Bader, Aldrees Mohammed, Alnaqa Ghaida... |
| 雑誌名 | The Saudi dental journal |
単一分子リアルタイムシーケンシングによるα-グロビン遺伝子クラスターの構造変異プロファイリング：中国人コホートで特異な希少変異と新規変異
Profiling structural variations of the α-globin gene cluster by the single molecule real-time sequencing: remarkable diversity of the spectrum with rare and novel variants identified in a large Chinese cohort.
書誌情報
| DOI | 10.1007/s00439-025-02801-6 |
|---|---|
| PMID | 41489826 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489826/ |
| 発行年 | 2026 |
| 著者名 | Wei Dan, Cheng Zifeng, Wei Wei, Gui Chunrong, Liu Juliang, Chen Hongfei, Ma... |
| 雑誌名 | Human genetics |
ブロッコリーの抵抗性を調査：BrRLP1-BrMDAR1の影響
The BrRLP1-BrMDAR1 module regulates the resistance to downy mildew in Brassica rapa.
書誌情報
| DOI | 10.1007/s00122-025-05108-2 |
|---|---|
| PMID | 41489841 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41489841/ |
| 発行年 | 2026 |
| 著者名 | Zhang Bin, Cao Yunyun, Zhang Bin, Tian Tian, Li Xiaoman, Li Peirong, Xin Xi... |
| 雑誌名 | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik |
慢性リンパ性白血病における免疫グロブリン重鎖状態と線維芽細胞相互作用がフェロプトーシス感受性を形成
Immunoglobulin heavy-chain status and stromal interactions shape ferroptosis sensitivity in chronic lymphocytic leukemia.
書誌情報
| DOI | 10.1038/s41392-025-02535-x |
|---|---|
| PMID | 41486278 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41486278/ |
| 発行年 | 2026 |
| 著者名 | Böttcher Martin, Reemts Lea, Hengeveld Paul J, Böttcher-Loschinski Romy, Bh... |
| 雑誌名 | Signal transduction and targeted therapy |
口腔扁平上皮癌のDNAメチル化解析
DNA methylation analysis of the epigenome in oral squamous cell carcinoma.
書誌情報
| DOI | 10.1186/s40246-025-00899-3 |
|---|---|
| PMID | 41486283 |
| PubMed URL | https://pubmed.ncbi.nlm.nih.gov/41486283/ |
| 発行年 | 2026 |
| 著者名 | Ma Jun, Huang Yu, Bai Yuxin, Zhou Na, Wang Hanxuan, Zhang Ying, Hu Min, Yan... |
| 雑誌名 | Human genomics |