2025.12.13

生体内の生理調節システムの開発

Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology.

書誌情報

DOI 10.1038/s41467-025-66347-x
PMID 41388022
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41388022/
発行年 2025
著者名 Vicencio Jeremy, Chihara Daisuke, Eder Matthias, Sedlackova Lucia, Ahringer...
雑誌名 Nature communications
2025.12.13

マントル細胞リンパ腫の進行に関与するスプライシング因子の同定と機能的特性

Identification and functional characterization of splicing factors implicated in mantle cell lymphoma aggressiveness.

書誌情報

DOI 10.1038/s41598-025-27512-w
PMID 41388034
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41388034/
発行年 2025
著者名 Yosudjai Juthamas, Poohadsuan Jirarat, Samart Parinya, Rodboon Napachai, Is...
雑誌名 Scientific reports
2025.12.13

SOX2陽性扁平細胞肺癌の治療標的

Utilising multi-modal data-driven network analysis to identify monotherapy and combinational therapy targets in SOX2-dependent squamous cell lung cancer.

書誌情報

DOI 10.1038/s42004-025-01778-7
PMID 41388088
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41388088/
発行年 2025
著者名 Hwang Woochang, Kottmann Daniel, Guo Wenrui, MacMahon Méabh, Correia Lucia,...
雑誌名 Communications chemistry
2025.12.12

N4BP2酵素による染色体破片化とecDNA形成

Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes.

書誌情報

DOI 10.1126/science.ado0977
PMID 41379955
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41379955/
発行年 2025
著者名 Krupina Ksenia, Goginashvili Alexander, Baughn Michael W, Moore Stephen, St...
雑誌名 Science (New York, N.Y.)
2025.12.12

パンゲノムの構造変異と集団サイズ

Multispecies pangenomes reveal a pervasive influence of population size on structural variation.

書誌情報

DOI 10.1126/science.adw1931
PMID 41379974
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41379974/
発行年 2025
著者名 Edwards Scott V, Fang Bohao, Khost Danielle, Kolyfetis George E, Cheek Rebe...
雑誌名 Science (New York, N.Y.)
2025.12.12

ドロソフィラの衛星DNA生物学の重要側面

Sequenced genomes and chromosome mapping illuminate key aspects of satellite DNA biology in Drosophila gouveai and D. borborema (buzzatii cluster, repleta group).

書誌情報

DOI 10.1590/1678-4685-GMB-2025-0133
PMID 41379991
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41379991/
発行年 2025
著者名 Rossi Anna C, Laborne Ana M, Barrios-Leal Dora Y, Manfrin Maura H, Kuhn Gus...
雑誌名 Genetics and molecular biology
2025.12.12

大豆の疫病抵抗性とイソフラボン

A balance between glycitein and glyceollins governed by isoflavone 6-hydroxylase confers soybean resistance to .

書誌情報

DOI 10.1073/pnas.2525627122
PMID 41380000
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41380000/
発行年 2025
著者名 Yang Qilin, Wang Yining, Xu Xindan, Yuan Jia, Zhang Fengxia, Qin Hao, Li Sh...
雑誌名 Proceedings of the National Academy of Sciences of the United States of America
2025.12.12

多発性骨髄腫のゲノム的潜在性

Genomically Smoldering Multiple Myeloma Is Not a Distinct Entity But a Collection of Monoclonal Gammopathy of Undetermined Significance or Multiple Myeloma.

書誌情報

DOI 10.1200/JCO-25-00289
PMID 41380103
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41380103/
発行年 2026
著者名 Aktas Samur Anil, Corre Jill, Talluri Srikanth, Shah Parth, Graffeuil Antoi...
雑誌名 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2025.12.12

アルドステロン欠損症の診断上の落とし穴:早期発症型疑似低アルドステロン症2型の9年間の追跡調査

Diagnostic pitfalls in aldosterone defects: a 9-year follow-up of early-onset pseudohypoaldosteronism type 2.

書誌情報

DOI 10.1515/jpem-2025-0526
PMID 41380172
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41380172/
発行年 2025
著者名 Cay Mevra, Turan Ihsan, Atmıs Bahriye, Kotan Leman Damla, Celebi Sukriye Tu...
雑誌名 Journal of pediatric endocrinology & metabolism : JPEM
2025.12.10

HLA-DQB1*03:01が独立してタイプ1ナルコレプシーの発症年齢に強く影響

HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity.

書誌情報

DOI 10.1073/pnas.2513989122
PMID 41364757
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364757/
発行年 2025
著者名 Zhang Lisan, Cai Shuo, Teng Ashton, Lin Ling, Han Fang, Yan Han, Hong Seung...
雑誌名 Proceedings of the National Academy of Sciences of the United States of America
2025.12.10

セントロメアクラスタリングと3次元ゲノム構造

Organization principles of dynamic three-dimensional genome architecture associated with centromere clustering states.

書誌情報

DOI 10.1073/pnas.2520310122
PMID 41364759
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364759/
発行年 2025
著者名 Polisetty Satya Dev, Dutta Shuvadip, Vadnala Rakesh Netha, Notani Dimple, P...
雑誌名 Proceedings of the National Academy of Sciences of the United States of America
2025.12.10

生物多様性データの影響:予測と記述の研究

Globally aggregated biodiversity data impact predictive and descriptive research.

書誌情報

DOI 10.1073/pnas.2519119122
PMID 41364761
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364761/
発行年 2025
著者名 Steinke Dirk, Gemeinholzer Birgit, Martínez-Meyer Enrique, Noesgaard Daniel...
雑誌名 Proceedings of the National Academy of Sciences of the United States of America
2025.12.10

A. baumanniiによる肺感染の細胞内貯蔵

Intracellular acts as a transient reservoir in lung infection via a "persist and resist" strategy.

書誌情報

DOI 10.1073/pnas.2511369122
PMID 41364768
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364768/
発行年 2025
著者名 Janet-Maitre Manon, Di Venanzio Gisela, Jackson-Litteken Clay D, Scott Nich...
雑誌名 Proceedings of the National Academy of Sciences of the United States of America
2025.12.10

多発性骨髄腫の腫瘍と免疫の長期的プロファイリング

Longitudinal profiling of tumor and immune compartments uncovers patterns of dysregulation and associations with response in multiple myeloma.

書誌情報

DOI 10.1158/2643-3230.BCD-25-0205
PMID 41364805
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364805/
発行年 2025
著者名 Ohlstrom Denis J, Pilcher William C, Michaud Marina E, Acharya Chaitanya, S...
雑誌名 Blood cancer discovery
2025.12.10

ツゲの遺伝子解析から見えた、神経酸の生合成と絶滅危惧種A. tsinglingenseの遺伝子の脆弱性

Comparative genomic analysis of Acer tsinglingense and A. davidii provides insights into nervonic acid biosynthesis, population evolution and genome vulnerability of endangered A. tsinglingense.

書誌情報

DOI 10.1111/tpj.70625
PMID 41364852
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41364852/
発行年 2025
著者名 Meng Xin, López-Pujol Jordi, Zhang Qi-Jing, Yue Ming, Li Zhong-Hu
雑誌名 The Plant journal : for cell and molecular biology