2026.01.14

肺扁平上皮癌における予後予測と免疫環境の特徴を示す新しい細胞外マトリックス離脱耐性関連遺伝子モデル

A novel anoikis resistance-associated gene model for prognostic prediction and immune microenvironment characterization in lung squamous cell carcinoma.

書誌情報

DOI 10.1007/s12672-026-04395-5
PMID 41530460
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530460/
発行年 2026
著者名 Ou Dong, Wang HongPing, Liu Yi, Nie Jin, Liu Daishun
雑誌名 Discover oncology
2026.01.14

MDアンダーソンでの早期臨床試験に参加した進行期非小細胞肺がん患者の治療反応

Therapeutic responses in patients with advanced NSCLC enrolled in early-phase clinical trials at MD Anderson.

書誌情報

DOI 10.1038/s41698-025-01261-5
PMID 41530472
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530472/
発行年 2026
著者名 Lim Jeong Uk, Lin Heather Y, Kang Lei, Le Hung, Tang Tin-Yun, Champiat Step...
雑誌名 NPJ precision oncology
2026.01.14

子宮頸がんのPD-1ブロックの個別化された影響

Unveiling personalised targets of PD-1 blockade hyperprogression in a cervical adenocarcinoma via longitudinal single-cell and spatial monitoring.

書誌情報

DOI 10.1038/s41698-025-01270-4
PMID 41530529
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530529/
発行年 2026
著者名 Su Zezhuo, Xiao Yue, Yang Li, Wang Yifu, Qu Yanling, Liu Junru, Tang Shunro...
雑誌名 NPJ precision oncology
2026.01.14

陰部癌患者における電気化学療法の研究

Electrochemotherapy as a symptom-oriented palliative treatment option: an exploratory single-center study in 15 patients with locally advanced or locoregionally recurrent vulvar carcinoma.

書誌情報

DOI 10.1007/s00404-025-08296-w
PMID 41530618
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41530618/
発行年 2026
著者名 Grischke Eva-Maria, Neis Felix, Oberlechner Ernst, Henes Melanie, Weiß Mart...
雑誌名 Archives of gynecology and obstetrics
2026.01.11

食道扁平上皮癌の腫瘍体積変化率と生存予後

Tumor volume change rate based on three-dimensional reconstruction as a predictor of pathological response and survival prognosis in esophageal squamous cell carcinoma with neoadjuvant immunochemotherapy.

書誌情報

DOI 10.1186/s12885-025-15497-8
PMID 41519689
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41519689/
発行年 2026
著者名 Ye Guanzhi, Pan Gaojian, Lin Shengrong, Jiang Jie, Zhu Xiaolei, Geng Guojun
雑誌名 BMC cancer
2026.01.11

腎細胞がんと脂肪酸パルミトイル化酵素

Comprehensive analysis of key palmitoylation-modifying enzymes in clear cell renal cell carcinoma: implications for prognosis and therapy.

書誌情報

DOI 10.1186/s12935-025-04155-5
PMID 41519750
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41519750/
発行年 2026
著者名 Li Guandu, Zhuge Yiduo, Xu Xinrui, Wang Jianhua, Zheng Zunwen, Che Xiangyu,...
雑誌名 Cancer cell international
2026.01.11

腫瘍関連マクロファージがPaclitaxelへの化学療法耐性を促進するメカニズム

Tumor-associated macrophages promote chemoresistance to Paclitaxel via activating NOTCH2-JAG1 juxtacrine signaling.

書誌情報

DOI 10.1186/s12943-025-02546-w
PMID 41519773
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41519773/
発行年 2026
著者名 Yu Fazhi, Zhou Qin, Yu Weiqiang, Zhou Tong, Cao Cheng, Xie Yijia, Zhang Pen...
雑誌名 Molecular cancer
2026.01.11

アラキドン酸によるピロプトーシスとミトファジーの非自己食機能による誘導が、PDACモデルにおける免疫療法を強化

Arachidonic acid induces pyroptosis via a non-autophagic function of mitophagy and enhances immunotherapy in a PDAC model.

書誌情報

DOI 10.1038/s41467-025-68267-2
PMID 41519804
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41519804/
発行年 2026
著者名 Chu Tongjia, Liu Ziyu, Liu Huan, Mu Wentao, Zhi Yao, Sheng Nan, Zhang Jian,...
雑誌名 Nature communications
2026.01.11

がん治療初期試験の拡大コホートの体系的レビュー

Expansion cohorts in phase 1 oncology trials: a systematic review of their design, implementation and outcomes.

書誌情報

DOI 10.1038/s41416-025-03334-5
PMID 41520059
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41520059/
発行年 2026
著者名 Herrero Colomina Julio, Hu Xinjie, Dinizulu Habana, Yan Ruiyang, Poles Eren...
雑誌名 British journal of cancer
2026.01.03

卵巣がんの細胞減少手術における脾摘出:術前の疾患予測と手術中の結果、抗菌予防と免疫接種の術後遵守

Splenectomy in Ovarian Cancer Cytoreductive Surgery: Pre-operative Prediction of Disease, Peri-operative Outcomes and Post-operative Adherence to Antimicrobial Prophylaxis and Immunisation.

書誌情報

DOI 10.21873/invivo.14193
PMID 41482400
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41482400/
発行年 2026
著者名 Corha Andrei, Graham Radha, Chandrasekaran Dhivya, Macdonald Nicola D, Dawa...
雑誌名 In vivo (Athens, Greece)
2026.01.03

肝硬変患者の脾動脈塞栓術の影響

Effect of Partial Splenic Embolization on Immune Environment and Hepatic Function in Cirrhosis Patients With Portal Hypertension.

書誌情報

DOI 10.21873/invivo.14201
PMID 41482406
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41482406/
発行年 2026
著者名 Ishikawa Toru, Sato Ryo, Natsui Hiroki, Iwasawa Takahiro, Ogawa Masahiro, K...
雑誌名 In vivo (Athens, Greece)
2026.01.03

肝がんにおけるCD48免疫チェックポイント

CD48 is a novel immune checkpoint on tumour-associated macrophages in hepatocellular carcinoma.

書誌情報

DOI 10.1136/gutjnl-2025-336744
PMID 41482455
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41482455/
発行年 2026
著者名 Shi Gege, Xiao Yang, Li Zhaozhao, Qiu Yueyuan, Zhou Yueyuan, Zhang Jieyu, L...
雑誌名 Gut
2026.01.03

死細胞関連抗原の交差提示と腫瘍免疫

Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity.

書誌情報

DOI 10.1038/s41590-025-02354-w
PMID 41482545
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41482545/
発行年 2026
著者名 Lim Kok Haw Jonathan, Schulz Oliver, Lobon Irene, Castro-Dopico Tomas, Zapa...
雑誌名 Nature immunology
2026.01.03

共刺激受容体改良によるT細胞生成の改善

Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors.

書誌情報

DOI 10.1038/s41551-025-01563-w
PMID 41482591
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41482591/
発行年 2026
著者名 Cabezas-Caballero Jose, Huhn Anna, Kutuzov Mikhail A, Andre Violaine, Shomu...
雑誌名 Nature biomedical engineering
2026.01.01

追加テリタシセプトが難治性眼筋無力症に改善効果

Add-On Telitacicept Significantly Improves Outcome of Patients With Refractory Ocular Myasthenia Gravis a Real-World Case Series.

書誌情報

DOI 10.1002/brb3.71157
PMID 41476025
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41476025/
発行年 2026
著者名 Lin Jing, Li Yue, Gui Mengcui, Bu Bitao, Li Zhijun
雑誌名 Brain and behavior