2026.01.01

pH刺激型ナノ反応器が腫瘍免疫療法を強化

pH-triggered Mn-ZIF8 nanoreactor enhances tumor immunotherapy by amplifying the cGAS-STING pathway through a self-reinforcing gas-metal synergy strategy.

書誌情報

DOI 10.1186/s12951-025-03950-6
PMID 41476198
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41476198/
発行年 2025
著者名 Wu Ziyi, Jiang Guangyao, Jiang Zhijie, Zhou Yanlin, Ji Yuqiao, Wang Lifan, ...
雑誌名 Journal of nanobiotechnology
2026.01.01

グリオーマにおける免疫療法の予測マッピング

Multimodality mapping of immunotherapy distribution as a predictive marker in glioma.

書誌情報

DOI 10.1093/neuonc/noaf295
PMID 41476211
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41476211/
発行年 2025
著者名 Scheck Jonas G, Boztepe Berin, Kernbach Julius M, Karimian-Jazi Kianush, He...
雑誌名 Neuro-oncology
2026.01.01

染色体調節因子変異と免疫療法の関連

Tumors with mutations in chromatin regulators are associated with higher mutational burden and improved response to checkpoint immunotherapy.

書誌情報

DOI 10.1186/s13148-025-02038-0
PMID 41476223
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41476223/
発行年 2025
著者名 Gjorgjievska Marija, Bukovec Djansel, Mehandziska Sanja, Risteski Milan, Ku...
雑誌名 Clinical epigenetics
2025.12.28

肝腫瘍に対する経動脈化学免疫塞栓療法におけるエピルビシンとTLR7アゴニストの持続放出を可能にする吸収性マイクロスフィア

Absorbable microspheres sustaining epirubicin and TLR7 agonist release for transarterial chemo-immuno-embolization in liver tumor.

書誌情報

DOI 10.1016/j.jconrel.2025.114576
PMID 41455500
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455500/
発行年 2026
著者名 Wang Yan, Guo Jiakun, Hu Di, Tan Hujing, Chen Wanting, Deng Chao, Zhu Xiaol...
雑誌名 Journal of controlled release : official journal of the Controlled Release Society
2025.12.28

転移性肺がんの治療法:グリシン誘導外膜小胞の利用

Pulmonary delivery of glycine-induced outer membrane vesicles as in situ vaccines for metastatic lung cancer.

書誌情報

DOI 10.1016/j.jconrel.2025.114578
PMID 41455501
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455501/
発行年 2025
著者名 Xu Wenwen, Wei Lu, Zhao Xing, Zhao Yuhan, Zhang Tian, Zhang Jingwen, Sun Si...
雑誌名 Journal of controlled release : official journal of the Controlled Release Society
2025.12.28

口腔扁平上皮癌におけるRUVBL1とmTORC1

RUVBL1-mediated mTORC1 activation drives tumour progression and immune evasion for oral squamous cell carcinoma.

書誌情報

DOI 10.1016/j.lfs.2025.124171
PMID 41455509
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455509/
発行年 2026
著者名 Wang Xinpei, Zhao Zuxuan, Jing Fengyang, Wang Bingzhi, Wang Meng, Ying Jian...
雑誌名 Life sciences
2025.12.28

上部消化器病理学の最新情報と課題(2026年)

What's new in upper gastrointestinal pathology: Key updates and evolving challenges in 2026.

書誌情報

DOI 10.1016/j.humpath.2025.106025
PMID 41455587
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455587/
発行年 2025
著者名 Ortiz Requena Domenika, Montgomery Elizabeth A
雑誌名 Human pathology
2025.12.28

免疫シナプスの最適な親和性とミトコンドリア修復が不均等細胞分裂とCAR T細胞の持続性を促す – レビュー

Optimal Avidity of the Immune Synapse and Mitochondrial Repair Trigger Asymmetrical Cell Division and CAR T Cell Persistence - Review.

書誌情報

DOI 10.1016/j.jtct.2025.12.988
PMID 41455592
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455592/
発行年 2025
著者名 Raychaudhuri Jyotishankar, Anasetti Claudio
雑誌名 Transplantation and cellular therapy
2025.12.28

イオン放出性生体材料の臨床研究への展望

The landscape of ion-releasing biomaterials: from preclinical insights to clinical studies.

書誌情報

DOI 10.1016/j.tibtech.2025.11.007
PMID 41455608
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455608/
発行年 2025
著者名 Li Qilin, Huang Shuo, Wu Ping
雑誌名 Trends in biotechnology
2025.12.28

がん細胞のピロプトーシスと細胞小器官:概要と展望

Organelles and cancer cell pyroptosis: overview and perspectives.

書誌情報

DOI 10.1038/s41419-025-08371-9
PMID 41455695
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455695/
発行年 2025
著者名 Qiu AnPeng, Lin JunDa, Hu HaoRan, Zhao ZiHou, Cai XinTong, Zhao Yuyue, Yu G...
雑誌名 Cell death & disease
2025.12.28

NSCLCにおけるCD4+ Tヘルパー細胞分化のエピジェネティックおよびエピトランスクリプトーム調節を微調整するRNAガイドのSTAT3修飾

RNA-guided STAT3 modification fine tunes the epigenetic and epitranscriptomic regulation of CD4 + T helper cell differentiation during non-small cell lung cancer (NSCLC).

書誌情報

DOI 10.1007/s12032-025-03230-1
PMID 41455873
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41455873/
発行年 2025
著者名 Bibi Roshni, George Melvin, Sarkar Koustav
雑誌名 Medical oncology (Northwood, London, England)
2025.12.23

皮膚がん治療:熱療と放射線療法

Skin cancer and hyperthermia and radiotherapy - SAHARA: study protocol for a multicenter, two-arm, open-label, randomized controlled phase II non-inferiority trial.

書誌情報

DOI 10.1186/s13063-025-09274-y
PMID 41430304
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41430304/
発行年 2025
著者名 Arnold Winfried, Sturz Maximilian, Batifi Nidar, Vaupel Peter, Notter Marku...
雑誌名 Trials
2025.12.23

免疫療法後の副鼻腔炎と難聴:報告と文献

Brief Communication: Severe Immuno-Induced Rhinosinusitis With Deafness After Ipilimumab and Nivolumab Combination for Melanoma, and Review of the Literature.

書誌情報

DOI 10.1097/CJI.0000000000000592
PMID 41430338
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41430338/
発行年 2025
著者名 Boyer Maëva, Kerimian Mélodie, Ribadeau Dumas Alix, Korbi Skander, Dutriaux...
雑誌名 Journal of immunotherapy (Hagerstown, Md. : 1997)
2025.12.11

抗体陽性の自己免疫脳炎:GAD65、GABAARΑ1、MGLUR5抗体を伴う1例と文献の検討

ANTIBODY-POSITIVE AUTOIMMUNE ENCEPHALITIS WITH ANTI-GAD65, ANTI-GABAARΑ1, AND ANTI-MGLUR5 ANTIBODIES: A CASE REPORT AND LITERATURE REVIEW.

書誌情報

PMID 41370676
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41370676/
発行年 2025
著者名 Peng Ting, Ge Hui, Tan Shidong, Fei Shizao
雑誌名 Georgian medical news
2025.12.11

結腸がん患者のプロルゴリマブ免疫療法

Neoadjuvant Immunotherapy With Prolgolimab in Patients With Locally Advanced Microsatellite Instability/Defective Mismatch Repair Colorectal Cancer.

書誌情報

DOI 10.1200/PO-25-00602
PMID 41370727
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41370727/
発行年 2025
著者名 Kuznetsova Olesya, Zagidullina Albina, Drobot Natalia, Prokopiev Aleksander...
雑誌名 JCO precision oncology