直近1年の新着論文: 7840件

2026.01.07 腸内細菌

西ヒマラヤの森林の季節変動と微生物

Seasonal shifts in vegetation, soil properties, and microbial communities in Western Himalayan forests.

書誌情報

DOI 10.1186/s40793-025-00842-y
PMID 41495863
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495863/
発行年 2026
著者名 Ali Huma, Rafiq Muhammad, Manzoor Muhammad, Gillani Syed Waseem, Degen Alla...
雑誌名 Environmental microbiome
2026.01.07 腸内細菌

植物病原菌におけるH3K27特異的メチルトランスフェラーゼによる病原性制御の研究

Facultative heterochromatin mediated by core and accessory chromosome-encoded H3K27-specific methyltransferases controls virulence in a fungal phytopathogen.

書誌情報

DOI 10.1093/nar/gkaf1441
PMID 41495884
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495884/
発行年 2026
著者名 Janevska Slavica, Gómez-Gil Lucía, Sae-Ong Tongta, Farooq Umer, Studt-Reinh...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

Lsm11のN末端ヘリックスがU7 snRNP内のCPSF73を安定化し、ヒストン前mRNAの3’末端処理を促進

An N-terminal helix of Lsm11 stabilizes CPSF73 in U7 snRNP for histone pre-mRNA 3'-end processing.

書誌情報

DOI 10.1093/nar/gkaf1442
PMID 41495886
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495886/
発行年 2026
著者名 Desotell Anthony, Marzluff William F, Dominski Zbigniew, Tong Liang
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

DNA統合のための高効率組換え酵素の進化誘導

Directed evolution on compact landing pads yields highly efficient recombinases for large DNA integration.

書誌情報

DOI 10.1093/nar/gkaf1444
PMID 41495889
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495889/
発行年 2026
著者名 Kim Hanseop, Kang Hyo-Gu, Oh Yeounsun, Lee Wi-Jae, Lee Youngjeon, Kim Eun-K...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

ショウジョウバエ転写因子のβストランド二量体化

Beyond DNA binding: single C2H2 zinc fingers with adjacent β-strands mediate dimerization in Drosophila transcription factors.

書誌情報

DOI 10.1093/nar/gkaf1425
PMID 41495890
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495890/
発行年 2026
著者名 Balagurov Konstantin I, Mariasina Sofia S, Dukhalin Sergey D, Sluchanko Nik...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

核キャップ結合複合体のRNA処理と監視

The nuclear cap-binding complex regulates subcellular RNA processing and surveillance of coding and noncoding RNAs.

書誌情報

DOI 10.1093/nar/gkaf1467
PMID 41495891
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495891/
発行年 2026
著者名 Ganguly Diep R, Gregory Brian D
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

ArgonauteによるRNA編集と点突然変異修復

Argonaute-mediated RNA editing selectively repairs point mutations.

書誌情報

DOI 10.1093/nar/gkaf1403
PMID 41495892
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495892/
発行年 2026
著者名 Zhang Zhiwei, Wang Jinyue, Guo Tongyu, Yu Xiaolan, Wang Fei, Zhang Hang, Li...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

RNAによるDNA転座を可能にするCRISPR-Cas影響因子の構造再配置

Sequential structural rearrangements at the PAM-distal site of a type I-F3 CRISPR-Cas effector enabling RNA-guided DNA transposition.

書誌情報

DOI 10.1093/nar/gkaf1415
PMID 41495894
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495894/
発行年 2026
著者名 Ishihara Kazuki, Matsumoto Shunsuke, Gerle Christoph, Gopalasingam Chai C, ...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

GIY-YIG核酸酵素の切断選好性の要因

Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.

書誌情報

DOI 10.1093/nar/gkaf1430
PMID 41495900
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495900/
発行年 2026
著者名 Loedige Kurt W, Hall Mairwyn A, Ghimirey Sabin, Stead Brent E, Edgell David...
雑誌名 Nucleic acids research
2026.01.07 遺伝子・ゲノム研究

特定の抗生物質耐性遺伝子を持つ大腸菌株の影響的な殺菌と再感受性向上の研究

Specific killing and resensitization of pathogenic Escherichia coli strains carrying blaCTX-M-15 β-lactamase using targeted-antibacterial-plasmids (TAPs).

書誌情報

DOI 10.1093/nar/gkaf1466
PMID 41495909
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495909/
発行年 2026
著者名 Derollez Elisabeth, Roson-Calero Natalia, Rouzé Pauline, Dedieu-Berne Annic...
雑誌名 Nucleic acids research
2026.01.07 医療AI

遺伝子リスクスコアと肥満関連死亡

A machine learning-derived polygenic risk score reveals that healthy lifestyle counteracts obesity-related mortality.

書誌情報

DOI 10.1038/s41746-025-02314-6
PMID 41495413
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495413/
発行年 2026
著者名 Xiao Lushan, Liang Shengxing, Zeng Lin, Cai Shumin, Wang Jiaren, Hong Chang...
雑誌名 NPJ digital medicine
2026.01.07 医療AI

≤2cm肺腺癌の微小乳頭状パターン予測モデル

Development of a Comprehensive Model Combining Clinical, Radiomics With Deep Learning for Predicting the Micropapillary Pattern in ≤2 cm Invasive Lung Adenocarcinoma.

書誌情報

DOI 10.1093/ejcts/ezag002
PMID 41495424
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495424/
発行年 2026
著者名 Hu Yang, Xiao Rong, Li Zhihao, He Wei
雑誌名 European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
2026.01.07 医療AI

早期非小細胞肺がん患者の個別条件付き生存予測

Personalized Conditional Survival Prediction for Patients with Early-Stage Non-small Cell Lung Cancer.

書誌情報

DOI 10.1245/s10434-025-18785-6
PMID 41495494
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495494/
発行年 2026
著者名 Chen Wei, Xue Xiangliang, Ma Jing, Li Yong
雑誌名 Annals of surgical oncology
2026.01.07 医療AI

薬剤データを用いた機械学習による人工呼吸の延長予測

Machine Learning-Based Prediction of Prolonged Duration of Mechanical Ventilation Using Medication Data.

書誌情報

DOI 10.1002/phar.70090
PMID 41495589
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495589/
発行年 2026
著者名 Murray Brian, Zhao Bokai, Chen Zhetao, Smith Susan E, Kong Yanlei, Shen Ye,...
雑誌名 Pharmacotherapy
2026.01.07 医療AI

HBsAg除去の機械学習予測について

Commentary on "Machine learning prediction of rapid HBsAg seroclearance at week 24 in inactive carriers treated with pegylated interferon.

書誌情報

DOI 10.1007/s12072-025-11007-x
PMID 41495599
PubMed URL https://pubmed.ncbi.nlm.nih.gov/41495599/
発行年 2026
著者名 Li Si, Guo Meihan, Ding Dapeng
雑誌名 Hepatology international