2026.01.07 腸内細菌

当帰芍薬散が脳血管性認知症ラットにおけるスフィンゴ脂質代謝を調整し、オリゴデンドロサイトの分化と成熟を促進

Danggui-Shaoyao-San modulates sphingolipid metabolism to promote oligodendrocyte differentiation and maturation in vascular dementia rats.

書誌情報

DOI	10.1186/s13020-025-01284-x
PMID	41495814
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495814/
発行年	2026
著者名	Su Yue, Zhong Yuying, Yuan Ningning, Li Xiang, Xu Ying, Yang Hui, Huang Men...
雑誌名	Chinese medicine

2026.01.07 腸内細菌

健康な人の腸内細菌多様性に及ぼすプロバイオティクス補充の影響：無作為化比較試験の体系的レビューとメタ分析

Effect of probiotic supplementation on the gut microbiota diversity in healthy populations: a systematic review and meta-analysis of randomised controlled trials.

書誌情報

DOI	10.1186/s12916-025-04602-0
PMID	41495831
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495831/
発行年	2026
著者名	Éliás Anna Júlia, Földvári-Nagy Kincső Csepke, Al-Gharati Yasmin Zubeida, V...
雑誌名	BMC medicine

2026.01.07 腸内細菌

Lactobacillus helveticus VEL12193が膜小胞を放出し、オートファジーを促進

The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles.

書誌情報

DOI	10.1186/s12964-025-02616-y
PMID	41495832
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495832/
発行年	2026
著者名	Bringer Marie-Agnès, Manceau Simon, Al Azzaz Jana, Buteau Bénédicte, Proukh...
雑誌名	Cell communication and signaling : CCS

2026.01.07 腸内細菌

西ヒマラヤの森林の季節変動と微生物

Seasonal shifts in vegetation, soil properties, and microbial communities in Western Himalayan forests.

書誌情報

DOI	10.1186/s40793-025-00842-y
PMID	41495863
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495863/
発行年	2026
著者名	Ali Huma, Rafiq Muhammad, Manzoor Muhammad, Gillani Syed Waseem, Degen Alla...
雑誌名	Environmental microbiome

2026.01.07 腸内細菌

植物病原菌におけるH3K27特異的メチルトランスフェラーゼによる病原性制御の研究

Facultative heterochromatin mediated by core and accessory chromosome-encoded H3K27-specific methyltransferases controls virulence in a fungal phytopathogen.

書誌情報

DOI	10.1093/nar/gkaf1441
PMID	41495884
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495884/
発行年	2026
著者名	Janevska Slavica, Gómez-Gil Lucía, Sae-Ong Tongta, Farooq Umer, Studt-Reinh...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

Lsm11のN末端ヘリックスがU7 snRNP内のCPSF73を安定化し、ヒストン前mRNAの3’末端処理を促進

An N-terminal helix of Lsm11 stabilizes CPSF73 in U7 snRNP for histone pre-mRNA 3'-end processing.

書誌情報

DOI	10.1093/nar/gkaf1442
PMID	41495886
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495886/
発行年	2026
著者名	Desotell Anthony, Marzluff William F, Dominski Zbigniew, Tong Liang
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

DNA統合のための高効率組換え酵素の進化誘導

Directed evolution on compact landing pads yields highly efficient recombinases for large DNA integration.

書誌情報

DOI	10.1093/nar/gkaf1444
PMID	41495889
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495889/
発行年	2026
著者名	Kim Hanseop, Kang Hyo-Gu, Oh Yeounsun, Lee Wi-Jae, Lee Youngjeon, Kim Eun-K...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

ショウジョウバエ転写因子のβストランド二量体化

Beyond DNA binding: single C2H2 zinc fingers with adjacent β-strands mediate dimerization in Drosophila transcription factors.

書誌情報

DOI	10.1093/nar/gkaf1425
PMID	41495890
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495890/
発行年	2026
著者名	Balagurov Konstantin I, Mariasina Sofia S, Dukhalin Sergey D, Sluchanko Nik...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

核キャップ結合複合体のRNA処理と監視

The nuclear cap-binding complex regulates subcellular RNA processing and surveillance of coding and noncoding RNAs.

書誌情報

DOI	10.1093/nar/gkaf1467
PMID	41495891
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495891/
発行年	2026
著者名	Ganguly Diep R, Gregory Brian D
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

ArgonauteによるRNA編集と点突然変異修復

Argonaute-mediated RNA editing selectively repairs point mutations.

書誌情報

DOI	10.1093/nar/gkaf1403
PMID	41495892
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495892/
発行年	2026
著者名	Zhang Zhiwei, Wang Jinyue, Guo Tongyu, Yu Xiaolan, Wang Fei, Zhang Hang, Li...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

RNAによるDNA転座を可能にするCRISPR-Cas影響因子の構造再配置

Sequential structural rearrangements at the PAM-distal site of a type I-F3 CRISPR-Cas effector enabling RNA-guided DNA transposition.

書誌情報

DOI	10.1093/nar/gkaf1415
PMID	41495894
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495894/
発行年	2026
著者名	Ishihara Kazuki, Matsumoto Shunsuke, Gerle Christoph, Gopalasingam Chai C, ...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

GIY-YIG核酸酵素の切断選好性の要因

Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.

書誌情報

DOI	10.1093/nar/gkaf1430
PMID	41495900
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495900/
発行年	2026
著者名	Loedige Kurt W, Hall Mairwyn A, Ghimirey Sabin, Stead Brent E, Edgell David...
雑誌名	Nucleic acids research

2026.01.07 遺伝子・ゲノム研究

特定の抗生物質耐性遺伝子を持つ大腸菌株の影響的な殺菌と再感受性向上の研究

Specific killing and resensitization of pathogenic Escherichia coli strains carrying blaCTX-M-15 β-lactamase using targeted-antibacterial-plasmids (TAPs).

書誌情報

DOI	10.1093/nar/gkaf1466
PMID	41495909
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495909/
発行年	2026
著者名	Derollez Elisabeth, Roson-Calero Natalia, Rouzé Pauline, Dedieu-Berne Annic...
雑誌名	Nucleic acids research

2026.01.07 医療AI

遺伝子リスクスコアと肥満関連死亡

A machine learning-derived polygenic risk score reveals that healthy lifestyle counteracts obesity-related mortality.

書誌情報

DOI	10.1038/s41746-025-02314-6
PMID	41495413
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495413/
発行年	2026
著者名	Xiao Lushan, Liang Shengxing, Zeng Lin, Cai Shumin, Wang Jiaren, Hong Chang...
雑誌名	NPJ digital medicine

2026.01.07 医療AI

≤2cm肺腺癌の微小乳頭状パターン予測モデル

Development of a Comprehensive Model Combining Clinical, Radiomics With Deep Learning for Predicting the Micropapillary Pattern in ≤2 cm Invasive Lung Adenocarcinoma.

書誌情報

DOI	10.1093/ejcts/ezag002
PMID	41495424
PubMed URL	https://pubmed.ncbi.nlm.nih.gov/41495424/
発行年	2026
著者名	Hu Yang, Xiao Rong, Li Zhihao, He Wei
雑誌名	European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery